Unmet medical need in under treated hyperuricemia associated with gout patients.
Large number of diagnosed, albeit untreated patients (9.8M); 30% (2.8M) are treated Gout in US:
• Of these, 50% (1.4M) are not well-controlled (uric acid >6 mg/dL) Treatment for Gout
• 1st line XOI drugs for Gout include allopurinol and to lesser extent febuxostat (black box warning)
• 12-35% (~1.6M) of diagnosed Gout patients have tophi; 0.16M are chronic refractory
• SAP-001 could be 1st line in this population